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Phyllanthus primarily contains lignans (e.g., phyllanthine and hypophyllanthine), alkaloids, and bioflavonoids (e.g., quercetin). While it remains unknown as to which of these ingredients has an antiviral effect, research shows this herb acts primarily on the liver. This action in the liver confirms its historical use as a remedy for jaundice. Phyllanthus blocks DNA polymerase, the enzyme needed for the hepatitis B virus to reproduce.
Research has utilized the powdered form of phyllanthus in amounts ranging from 900-2,700mg per day for three months.[5] No side effects have been reported using phyllanthus as recommended, and there are currently no well-known drug interactions with phyllanthus. J Lab Clin Med 1995;126: pp.350-2
[5] Reichert R. Phytotherapeutic alternatives for chronic hepatitis. Quart Rev Natural Med 1997;Summer: pp.103-8.
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