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| The systemic forms can affect any part of the body (skin, blood vessels, and internal organs.) They are also referred to as "systemic sclerosis" plus other terms such as diffuse, limited, CREST, and overlap. When systemic scleroderma affects the skin, it can cause the skin - most commonly on the hands and/or face - to harden. Limited scleroderma is when skin involvement is limited to the hands (although the face and neck may also be involved.) CREST stands for Calcinosis, Raynaud's, Esophagus, Sclerodactyly, and Telangiectasia. Treatment At present, there are no proven treatments or cure for any forms of scleroderma. However, there are effective therapies for many of the symptoms. Research shows that Raynaud's can cause an abnormal processing of certain vitamins and minerals, leading to worsening scleroderma. |
| DMSO Topically Vitamin Paba |