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Serum copper levels in these patients are abnormally high. Since copper is a brain stimulant and destroys histamine, the elevated serum (and presumably brain) copper level probably accounts for many symptoms, including the low blood histamine level. Behavioral symptoms in high-copper histapenia include paranoia and hallucinations in younger patients, but depression may predominate in older patients. The patient is usually classified as having chronic or process schizophrenia.
Some studies of schizophrenics have revealed high blood copper, as seen in histadelia, with low urinary copper (showing that copper is being retained) as well as low blood zinc. With this treatment the high blood copper is slowly reduced and symptoms are slowly relieved in several months' time. |
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