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Unlike acute renal failure with its sudden (but reversible) failure of kidney function, chronic renal failure is slowly progressive. Chronic renal failure usually occurs over a number of years as the internal structures of the kidney are slowly destroyed. Causative diseases include glomerulonephritis of any type (one of the most common causes), polycystic kidney disease, hypertension, Alport syndrome, reflux nephropathy, obstruction, kidney stones, infection, and analgesic toxicity. Chronic renal failure results in the accumulation of fluid and waste products in the body, causing low urine output and waste accumulation. Treatment of the underlying disorders may help prevent or delay development of chronic renal failure. There is no cure for chronic renal failure. Dialysis or kidney transplant may eventually be required. |
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